PRODUCT DETAILS

About Agopride Injection

LEUPROLIDE belongs to the class of 'anticancer or anti-neoplastic agents', primarily used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. Prostate cancer is the prostate gland's cancer (a small gland under the bladder secretes fluid that nourishes and protects sperm) found only in men. Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Endometriosis is a disorder in which tissue lining the uterus grows outside the uterine cavity. Precocious puberty occurs when a child's body changes into that of an adult or experiences puberty too soon.

Uses of Agopride Injection

Prostate cancer, Breast cancer, Endometriosis, Precocious puberty

Medicinal Benefits of Agopride Injection

LEUPROLIDE contains Leuprolide, a gonadotropin-releasing hormone (GnRH) agonist. It treats prostate cancer in men, endometriosis in women and precocious puberty (early puberty) in children. LEUPROLIDE is a synthetic hormone that acts similar to the GnRH, produced by the hypothalamus gland in the brain. Being an anti-neoplastic or anticancer agent, LEUPROLIDE works by lowering testosterone levels in men that help stop the growth of cancer cells in prostate cancer. LEUPROLIDE reduces oestrogen (a hormone required for the development and regulation of the female reproductive system and secondary sexual characteristics) levels in women, thus helps in shrinking of endometriosis and breast cancer.

Directions for Use

Injection: LEUPROLIDE will be administered by a healthcare professional. Do not self-administer. Based on your medical condition, your doctor will decide how long you need to take LEUPROLIDE.

Side Effects of Agopride Injection

• Weight changes
• Hot flushes
• Muscle weakness
• Bone Pain
• Loss of interest in sexual intercourse
• Inability to have an erection
• Tiredness
• Difficulty sleeping
• Headaches
• Breast tenderness
• Changes in breast size
• Mood swings
• Abdominal pain
• Vomiting (feeling sick)
• Acne
• Vaginal Bleeding 
• Spotting
• Injection site reactions (skin hardening, redness, pain, abscesses, swelling, nodules, ulcers and skin damage)

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to LEUPROLIDE or any other medicines, please tell your doctor. LEUPROLIDE can affect the unborn baby when used in pregnancy. Hence, LEUPROLIDE is not indicated for use in pregnancy and breastfeeding women. If you are using LEUPROLIDE, make sure to use reliable forms of contraception to prevent pregnancy during the course. LEUPROLIDE may also affect fertility in men, hence discuss with your doctor if you have any plans to start a family in the future. Use the LEUPROLIDE with caution in elderly patients and children. LEUPROLIDE is not recommended for children younger than two years of age. Your symptoms may become temporarily worse when you first start taking LEUPROLIDE. Inform your doctor if this continues for longer than 2 months. If you have a seizure or unusual changes in mood or behaviour, inform your doctor immediately. Before starting LEUPROLIDE, let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels. LEUPROLIDE may cause QT prolongation (heart muscle takes longer than normal to recharge between beats) and may affect heart rhythm, hence heart patients should be cautious while taking LEUPROLIDE. LEUPROLIDE can make you feel dizzy and affects your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused.

Drug Interactions

Drug-Drug Interaction:

 LEUPROLIDE may interact with heart rhythm problems treating drugs (quinidine, procainamide, disopyramide, amiodarone, sotalol), steroids (dexamethasone, methylprednisolone) and prednisone antibiotics (moxifloxacin), opioid pain killers (methadone) and antipsychotics (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline).

Drug-Disease Interaction:

 LEUPROLIDE should be used with caution in cases of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels.

Safety Advice

ALCOHOL

• You are recommended to avoid alcohol consumption while taking LEUPROLIDE to avoid unpleasant side-effects. Alcohol intake, along with LEUPROLIDE, may cause increased drowsiness.

PREGNANCY

• LEUPROLIDE is a pregnancy category X drug. LEUPROLIDE should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective method of contraception while taking fluorouracil and for at least 6 months afterwards. Please consult your doctor about any concerns regarding this.

BREAST FEEDING

• LEUPROLIDE should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

DRIVING

• LEUPROLIDE causes dizziness and affects your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with LEUPROLIDE.

LIVER

• If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking LEUPROLIDE. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

KIDNEY

• If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking LEUPROLIDE. Your doctor will weigh the benefits and any potential risks before prescribing it to you.